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| 21:30 | Tigre-ARG | 0 2x0 0 | Alianza Atletico-PER | 74 | 18 | 08 | 1.27 | 5.19 | 11.60 |  | | 21:30 | America Cali-COL | 0 0x0 0 | Macara-ECU | 57 | 27 | 16 | 1.65 | 3.50 | 5.59 | |
| 21:30 | River Plate-PAR | 0 3x0 0 | Blooming-BOL | 88 | 09 | 03 | 1.08 | 10.25 | 26.96 | | | 21:30 | Red Bull Bragantino/SP-BRA | 0 2x0 0 | Carabobo-VEN | 71 | 20 | 09 | 1.32 | 4.76 | 10.15 | | | 19:00 | Vasco da Gama/RJ-BRA | 2 3x0 0 | Barracas Central-ARG | 70 | 19 | 11 | 1.35 | 4.87 | 8.35 | | | 19:00 | Racing Club-ARG | 1 2x0 0 | Indep Petroleros-BOL | 87 | 09 | 04 | 1.08 | 9.94 | 23.76 | | | 19:00 | Olimpia-PAR | 0 3x1 0 | Audax Italiano-CHI | 59 | 24 | 17 | 1.60 | 3.97 | 5.29 | | | 19:00 | Cienciano-PER | 1 1x1 0 | Juventud LP-URU | 59 | 24 | 17 | 1.59 | 3.95 | 5.45 | | | 19:00 | Caracas FC-VEN | 1 1x3 0 | Botafogo/RJ-BRA | 27 | 30 | 43 | 3.47 | 3.10 | 2.18 | | | 19:00 | Atletico/MG-BRA | 0 1x0 0 | Puerto Cabello-VEN | 74 | 18 | 08 | 1.27 | 5.20 | 11.33 | |
| 21:30 | Santos/SP-BRA | 1 3x0 0 | Deportivo Cuenca-ECU | 69 | 20 | 11 | 1.37 | 4.80 | 8.28 | | | 21:30 | San Lorenzo-ARG | 0 0x1 1 | Deportivo Recoleta-PAR | 68 | 21 | 11 | 1.37 | 4.40 | 8.91 | | | 19:00 | Sao Paulo/SP-BRA | 2 2x0 0 | Boston River-URU | 76 | 16 | 08 | 1.25 | 6.04 | 10.90 | | | 19:00 | Palestino-CHI | 1 1x1 1 | Deportivo Riestra-ARG | 40 | 30 | 30 | 2.35 | 3.16 | 3.12 | | | 19:00 | Millonarios-COL | 0 1x2 2 | O Higgins-CHI | 58 | 25 | 17 | 1.62 | 3.79 | 5.49 | | | 19:00 | Gremio/RS-BRA | 0 2x2 1 | City Torque-URU | 61 | 24 | 15 | 1.55 | 3.89 | 6.25 | |
| 23:00 | Macara-ECU | 0 0x0 0 | Alianza Atletico-PER | 57 | 25 | 18 | 1.65 | 3.75 | 4.95 | | | 21:30 | Blooming-BOL | 0 0x2 1 | Carabobo-VEN | 27 | 28 | 45 | 3.41 | 3.35 | 2.10 | | | 21:00 | Racing Club-ARG | 2 2x2 1 | Caracas FC-VEN | 80 | 14 | 06 | 1.17 | 6.66 | 14.13 | | | 19:00 | Puerto Cabello-VEN | 1 1x1 1 | Juventud LP-URU | 43 | 29 | 28 | 2.20 | 3.22 | 3.29 | | | 19:00 | Atletico/MG-BRA | 2 2x0 0 | Cienciano-PER | 79 | 15 | 06 | 1.18 | 6.29 | 13.68 | |
| 21:30 | River Plate-PAR | 0 1x1 1 | Red Bull Bragantino/SP-BRA | 51 | 28 | 21 | 1.84 | 3.35 | 4.40 | | | 21:00 | Indep Petroleros-BOL | 0 0x3 1 | Botafogo/RJ-BRA | 09 | 15 | 76 | 11.02 | 6.08 | 1.22 | | | 21:00 | Gremio/RS-BRA | 1 2x0 0 | Palestino-CHI | 68 | 20 | 12 | 1.38 | 4.55 | 7.75 | | | 19:00 | Santos/SP-BRA | 2 2x2 0 | San Lorenzo-ARG | 53 | 27 | 20 | 1.78 | 3.50 | 4.58 | | | 19:00 | Olimpia-PAR | 0 3x1 1 | Vasco da Gama/RJ-BRA | 39 | 30 | 31 | 2.39 | 3.16 | 3.02 | | | 19:00 | Boston River-URU | 2 3x2 0 | O Higgins-CHI | 24 | 29 | 47 | 3.89 | 3.27 | 1.98 | |
| 23:00 | Deportivo Cuenca-ECU | 1 2x2 2 | Deportivo Recoleta-PAR | 57 | 26 | 17 | 1.63 | 3.60 | 5.57 | | | 23:00 | America Cali-COL | 0 1x1 1 | Tigre-ARG | 47 | 29 | 24 | 2.00 | 3.24 | 3.89 | | | 21:30 | Sao Paulo/SP-BRA | 1 1x1 0 | Millonarios-COL | 58 | 26 | 16 | 1.62 | 3.64 | 5.82 | | | 19:00 | City Torque-URU | 2 4x1 0 | Deportivo Riestra-ARG | 43 | 30 | 27 | 2.18 | 3.12 | 3.47 | | | 19:00 | Audax Italiano-CHI | 1 2x0 0 | Barracas Central-ARG | 39 | 29 | 32 | 2.39 | 3.22 | 2.97 | |
| 21:30 | Carabobo-VEN | 0 1x2 0 | River Plate-PAR | 21 | 29 | 50 | 4.38 | 3.25 | 1.87 | | | 21:30 | Blooming-BOL | 0 0x6 3 | Red Bull Bragantino/SP-BRA | 23 | 26 | 51 | 4.07 | 3.62 | 1.83 | | | 19:00 | O Higgins-CHI | 0 0x0 0 | Sao Paulo/SP-BRA | 33 | 30 | 37 | 2.83 | 3.10 | 2.54 | | | 19:00 | Boston River-URU | 1 2x4 0 | Millonarios-COL | 21 | 28 | 51 | 4.29 | 3.39 | 1.85 | |
| 23:00 | Alianza Atletico-PER | 0 0x2 0 | America Cali-COL | 29 | 29 | 42 | 3.25 | 3.20 | 2.24 | | | 21:30 | Botafogo/RJ-BRA | 1 2x1 0 | Racing Club-ARG | 42 | 29 | 29 | 2.24 | 3.22 | 3.25 | | | 21:00 | Macara-ECU | 1 2x2 1 | Tigre-ARG | 37 | 32 | 31 | 2.54 | 2.97 | 2.99 | | | 21:00 | Barracas Central-ARG | 1 1x2 1 | Olimpia-PAR | 32 | 32 | 36 | 2.87 | 2.95 | 2.62 | | | 19:00 | City Torque-URU | 0 1x0 0 | Palestino-CHI | 51 | 28 | 21 | 1.86 | 3.39 | 4.28 | | | 19:00 | Audax Italiano-CHI | 1 1x2 0 | Vasco da Gama/RJ-BRA | 37 | 30 | 33 | 2.58 | 3.16 | 2.77 | |
| 23:00 | Deportivo Cuenca-ECU | 0 0x0 0 | San Lorenzo-ARG | 38 | 30 | 32 | 2.47 | 3.14 | 2.89 | | | 21:30 | Puerto Cabello-VEN | 1 3x0 0 | Cienciano-PER | 47 | 28 | 25 | 2.00 | 3.37 | 3.74 | | | 21:30 | Deportivo Recoleta-PAR | 0 1x1 1 | Santos/SP-BRA | 15 | 23 | 62 | 6.54 | 4.00 | 1.51 | | | 19:00 | Juventud LP-URU | 0 2x2 1 | Atletico/MG-BRA | 28 | 28 | 44 | 3.37 | 3.29 | 2.12 | | | 19:00 | Indep Petroleros-BOL | 0 2x3 2 | Caracas FC-VEN | 41 | 28 | 31 | 2.27 | 3.29 | 3.06 | | | 19:00 | Deportivo Riestra-ARG | 0 0x3 1 | Gremio/RS-BRA | 34 | 33 | 33 | 2.75 | 2.83 | 2.83 | |
| 23:00 | Alianza Atletico-PER | 0 0x2 2 | Macara-ECU | 39 | 33 | 28 | 2.39 | 2.85 | 3.35 | | | 21:30 | Red Bull Bragantino/SP-BRA | 0 0x1 0 | River Plate-PAR | 35 | 31 | 34 | 2.72 | 2.97 | 2.72 | | | 21:00 | Tigre-ARG | 2 2x0 0 | America Cali-COL | 50 | 30 | 20 | 1.88 | 3.16 | 4.48 | | | 19:00 | Vasco da Gama/RJ-BRA | 1 3x0 0 | Olimpia-PAR | 50 | 27 | 23 | 1.87 | 3.45 | 4.09 | | | 19:00 | Carabobo-VEN | 2 2x0 0 | Blooming-BOL | 56 | 25 | 19 | 1.67 | 3.68 | 4.91 | |
| 21:30 | Palestino-CHI | 0 0x0 0 | Gremio/RS-BRA | 30 | 31 | 39 | 3.04 | 3.04 | 2.43 | | | 21:30 | Cienciano-PER | 1 1x0 0 | Atletico/MG-BRA | 50 | 27 | 23 | 1.87 | 3.45 | 4.19 | | | 19:00 | Juventud LP-URU | 4 4x0 0 | Puerto Cabello-VEN | 45 | 30 | 25 | 2.08 | 3.10 | 3.83 | | | 19:00 | Deportivo Riestra-ARG | 2 2x1 1 | City Torque-URU | 43 | 31 | 26 | 2.20 | 3.02 | 3.54 | | | 19:00 | Caracas FC-VEN | 0 1x1 1 | Racing Club-ARG | 19 | 27 | 54 | 4.80 | 3.50 | 1.76 | |
| 23:00 | O Higgins-CHI | 1 2x0 0 | Boston River-URU | 56 | 26 | 18 | 1.68 | 3.54 | 5.04 | | | 21:30 | Millonarios-COL | 0 0x0 0 | Sao Paulo/SP-BRA | 38 | 30 | 32 | 2.49 | 3.06 | 2.89 | | | 21:30 | Deportivo Recoleta-PAR | 0 0x0 0 | Deportivo Cuenca-ECU | 36 | 31 | 33 | 2.58 | 3.02 | 2.83 | | | 21:00 | Barracas Central-ARG | 1 1x1 0 | Audax Italiano-CHI | 51 | 28 | 21 | 1.84 | 3.33 | 4.36 | | | 19:00 | San Lorenzo-ARG | 1 1x1 1 | Santos/SP-BRA | 41 | 32 | 27 | 2.29 | 2.95 | 3.35 | | | 19:00 | Botafogo/RJ-BRA | 1 3x0 0 | Indep Petroleros-BOL | 85 | 10 | 05 | 1.10 | 9.18 | 20.05 | |
| 23:00 | Cienciano-PER | 1 2x0 0 | Puerto Cabello-VEN | 63 | 22 | 15 | 1.50 | 4.33 | 5.87 | | | 21:30 | San Lorenzo-ARG | 0 2x0 0 | Deportivo Cuenca-ECU | 60 | 28 | 12 | 1.57 | 3.33 | 7.70 | | | 21:30 | Red Bull Bragantino/SP-BRA | 1 3x2 1 | Blooming-BOL | 77 | 16 | 07 | 1.22 | 5.96 | 11.74 | | | 19:00 | Tigre-ARG | 0 0x1 0 | Macara-ECU | 59 | 26 | 15 | 1.59 | 3.64 | 6.12 | | | 19:00 | Atletico/MG-BRA | 1 2x1 0 | Juventud LP-URU | 73 | 18 | 09 | 1.29 | 5.30 | 9.28 | |
| 23:00 | Millonarios-COL | 0 1x0 0 | Boston River-URU | 77 | 16 | 07 | 1.21 | 5.84 | 13.85 | | | 23:00 | America Cali-COL | 1 2x1 1 | Alianza Atletico-PER | 68 | 21 | 11 | 1.38 | 4.54 | 7.95 | | | 21:30 | River Plate-PAR | 0 1x0 0 | Carabobo-VEN | 77 | 16 | 07 | 1.22 | 5.82 | 13.16 | | | 21:00 | Olimpia-PAR | 0 0x0 0 | Barracas Central-ARG | 54 | 28 | 18 | 1.75 | 3.33 | 5.12 | | | 19:00 | Racing Club-ARG | 1 2x3 2 | Botafogo/RJ-BRA | 50 | 28 | 22 | 1.87 | 3.31 | 4.41 | | | 19:00 | Caracas FC-VEN | 0 1x0 0 | Indep Petroleros-BOL | 63 | 24 | 13 | 1.50 | 3.93 | 7.11 | |
| 21:30 | Santos/SP-BRA | 1 1x1 1 | Deportivo Recoleta-PAR | 73 | 19 | 08 | 1.29 | 4.83 | 11.16 | | | 21:30 | Palestino-CHI | 0 0x2 1 | City Torque-URU | 42 | 28 | 30 | 2.20 | 3.35 | 3.10 | | | 21:00 | Vasco da Gama/RJ-BRA | 1 1x2 0 | Audax Italiano-CHI | 68 | 19 | 13 | 1.37 | 4.83 | 7.12 | | | 19:00 | Sao Paulo/SP-BRA | 1 2x0 0 | O Higgins-CHI | 71 | 21 | 08 | 1.32 | 4.54 | 10.80 | | | 19:00 | Gremio/RS-BRA | 0 1x0 0 | Deportivo Riestra-ARG | 64 | 25 | 11 | 1.46 | 3.70 | 8.47 | |
| 21:30 | Macara-ECU | 1 1x1 1 | America Cali-COL | 27 | 35 | 38 | 3.35 | 2.66 | 2.49 | | | 21:30 | Carabobo-VEN | 1 1x0 0 | Red Bull Bragantino/SP-BRA | 25 | 30 | 45 | 3.75 | 3.15 | 2.15 | | | 19:00 | Juventud LP-URU | 1 1x1 0 | Cienciano-PER | 44 | 28 | 28 | 2.14 | 3.27 | 3.33 | | | 19:00 | Botafogo/RJ-BRA | 0 1x1 1 | Caracas FC-VEN | 75 | 17 | 08 | 1.26 | 5.62 | 10.42 | |
| 23:00 | Puerto Cabello-VEN | 2 2x1 1 | Atletico/MG-BRA | 20 | 29 | 51 | 4.54 | 3.22 | 1.86 | | | 21:30 | City Torque-URU | 0 1x0 0 | Gremio/RS-BRA | 28 | 30 | 42 | 3.39 | 3.08 | 2.22 | | | 21:30 | Blooming-BOL | 0 1x1 1 | River Plate-PAR | 13 | 20 | 67 | 6.95 | 4.69 | 1.39 | | | 21:00 | Audax Italiano-CHI | 0 0x2 2 | Olimpia-PAR | 32 | 33 | 35 | 2.89 | 2.83 | 2.70 | | | 19:00 | Deportivo Cuenca-ECU | 0 1x0 0 | Santos/SP-BRA | 40 | 31 | 29 | 2.37 | 3.04 | 3.14 | | | 19:00 | Deportivo Recoleta-PAR | 1 1x1 1 | San Lorenzo-ARG | 21 | 30 | 49 | 4.44 | 3.10 | 1.91 | | | 19:00 | Deportivo Riestra-ARG | 0 0x0 0 | Palestino-CHI | 50 | 31 | 19 | 1.89 | 3.02 | 4.71 | |
| 23:00 | Alianza Atletico-PER | 0 1x1 1 | Tigre-ARG | 22 | 31 | 47 | 4.23 | 3.06 | 1.98 | | | 21:30 | Boston River-URU | 0 0x1 0 | Sao Paulo/SP-BRA | 16 | 26 | 58 | 5.86 | 3.58 | 1.62 | | | 21:00 | O Higgins-CHI | 1 2x0 0 | Millonarios-COL | 39 | 32 | 29 | 2.43 | 2.97 | 3.12 | | | 19:00 | Indep Petroleros-BOL | 1 1x3 2 | Racing Club-ARG | 17 | 23 | 60 | 5.58 | 4.00 | 1.57 | | | 19:00 | Barracas Central-ARG | 0 0x0 0 | Vasco da Gama/RJ-BRA | 51 | 28 | 21 | 1.85 | 3.31 | 4.44 | |
| 23:00 | Orense-ECU | 0 0x1 0 | Macara-ECU | 48 | 31 | 21 | 1.95 | 3.04 | 4.28 | | | 21:30 | Cienciano-PER | 0 1x1 0 | FBC Melgar-PER | 38 | 28 | 34 | 2.43 | 3.31 | 2.72 | | | 21:30 | America Cali-COL | 1 2x1 1 | Atletico Bucaramanga-COL | 44 | 31 | 25 | 2.12 | 2.97 | 3.75 | | | 19:00 | Nacional Asuncion-PAR | 0 1x1 1 | Deportivo Recoleta-PAR | 52 | 28 | 20 | 1.78 | 3.29 | 4.76 | | | 19:00 | Boston River-URU | 0 1x0 0 | Racing Club-URU | 32 | 32 | 36 | 2.95 | 2.87 | 2.56 | |
| 23:00 | Deportivo Cuenca-ECU | 1 3x0 0 | Libertad-ECU | 53 | 28 | 19 | 1.75 | 3.29 | 5.05 | | | 21:30 | Univ de Chile-CHI | 0 1x2 0 | Palestino-CHI | 58 | 25 | 17 | 1.62 | 3.70 | 5.29 | | | 21:30 | Sportivo Trinidense-PAR | 0 0x1 1 | Olimpia-PAR | 24 | 29 | 47 | 3.85 | 3.22 | 1.97 | | | 21:30 | Atletico Nacional-COL | 1 1x3 2 | Millonarios-COL | 59 | 26 | 15 | 1.58 | 3.60 | 6.21 | | | 19:00 | Caracas FC-VEN | 0 0x0 0 | Metropolitanos-VEN | 42 | 30 | 28 | 2.22 | 3.14 | 3.27 | | | 19:00 | Blooming-BOL | 0 3x0 0 | San Antonio-BOL | 61 | 21 | 18 | 1.52 | 4.46 | 5.17 | |
| 23:00 | Alianza Atletico-PER | 1 2x0 0 | Deportivo Garcilaso-PER | 44 | 31 | 25 | 2.12 | 2.99 | 3.68 | | | 21:30 | Puerto Cabello-VEN | 0 0x0 0 | Monagas-VEN | 48 | 28 | 24 | 1.94 | 3.25 | 3.89 | | | 21:30 | Cobresal-CHI | 0 1x1 1 | Audax Italiano-CHI | 41 | 29 | 30 | 2.27 | 3.22 | 3.06 | | | 19:00 | Indep Petroleros-BOL | 0 0x0 0 | Guabira-BOL | 45 | 26 | 29 | 2.06 | 3.62 | 3.18 | | | 19:00 | City Torque-URU | 0 1x0 0 | Defensor Sporting-URU | 44 | 31 | 25 | 2.12 | 3.00 | 3.68 | |
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