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| 23:30 | LA Galaxy | 1 3x0 0 | Vancouver Whitecaps | 38 | 26 | 36 | 2.49 | 3.60 | 2.62 |  | | 22:30 | Colorado | 0 1x2 1 | Sporting Kansas City | 50 | 24 | 26 | 1.87 | 3.89 | 3.68 | |
| 22:00 | Palmeiras/SP | 0 1x2 1 | Chelsea | 25 | 29 | 46 | 3.81 | 3.29 | 2.06 | |
| 21:45 | Dallas | 0 1x2 1 | Minnesota United | 32 | 27 | 41 | 2.85 | 3.54 | 2.33 | |
| 21:00 | Libertad | 0 2x1 1 | Deportivo Cuenca | 40 | 28 | 32 | 2.33 | 3.24 | 2.87 | |
| 19:00 | Coritiba/PR | 2 2x0 0 | Volta Redonda/RJ | 56 | 28 | 16 | 1.65 | 3.29 | 5.95 | |
| 18:30 | Deportivo Recoleta | 1 2x4 4 | Sportivo Trinidense | 30 | 29 | 41 | 3.08 | 3.16 | 2.22 | |
| 17:15 | CD Los Chankas | 1 1x1 0 | AD Tarma | 38 | 28 | 34 | 2.47 | 3.33 | 2.68 | |
| 16:00 | Fluminense/RJ | 1 2x1 0 | Al Hilal Riyadh | 33 | 29 | 38 | 2.85 | 3.33 | 2.50 | |
| 15:45 | St Patricks | 0 0x0 0 | Bohemians FC | 39 | 29 | 32 | 2.41 | 3.20 | 2.87 | | | 15:45 | Shelbourne Fc | 2 3x1 1 | Cork City | 61 | 24 | 15 | 1.54 | 3.89 | 5.92 | | | 15:45 | Drogheda Utd | 0 1x0 0 | Galway United | 36 | 29 | 35 | 2.60 | 3.16 | 2.64 | | | 15:45 | Derry City | 4 7x2 0 | Waterford FC | 60 | 24 | 16 | 1.55 | 3.89 | 5.76 | |
| 15:00 | Sport Huancayo | 1 1x0 0 | UTC Cajamarca | 62 | 22 | 16 | 1.50 | 4.13 | 5.95 | |
| 12:30 | JaPS | x | SalPa Salo | 58 | 22 | 20 | 1.58 | 4.19 | 4.62 | |
| 12:00 | AC Oulu | 1 2x2 0 | KuPS | 24 | 25 | 51 | 3.91 | 3.72 | 1.83 | |
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