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| 23:00 | Once Caldas-COL | 1 1x0 0 | Union Espanola-CHI | 60 | 24 | 16 | 1.57 | 3.91 | 5.62 |  |
| 23:00 | Sporting Cristal-PER | 1 2x1 0 | Bolivar-BOL | 47 | 25 | 28 | 2.02 | 3.72 | 3.37 | |
| 22:00 | Monterrey | 1 3x2 1 | Toluca | 43 | 29 | 28 | 2.20 | 3.30 | 3.40 | |
| 21:30 | Mushuc Ruma-ECU | 0 1x1 0 | Cruzeiro/MG-BRA | 50 | 27 | 23 | 1.87 | 3.49 | 4.00 | | | 21:30 | Atletico Grau-PER | 0 0x0 0 | Gremio/RS-BRA | 18 | 26 | 56 | 4.98 | 3.60 | 1.68 | |
| 21:30 | Cerro Porteno-PAR | 0 0x2 1 | Palmeiras/SP-BRA | 22 | 28 | 50 | 4.36 | 3.31 | 1.88 | | | 21:30 | Central Cordoba-ARG | 0 1x1 1 | Flamengo/RJ-BRA | 18 | 27 | 55 | 5.19 | 3.43 | 1.72 | | | 21:00 | Univ de Chile-CHI | 0 0x3 3 | Estudiantes-ARG | 40 | 31 | 29 | 2.39 | 3.00 | 3.20 | |
| 19:00 | Union Santa Fe-ARG | 0 1x2 0 | Palestino-CHI | 57 | 25 | 18 | 1.63 | 3.68 | 5.25 | | | 19:00 | Puerto Cabello-VEN | 1 4x1 1 | Vasco da Gama/RJ-BRA | 18 | 25 | 57 | 5.12 | 3.77 | 1.64 | | | 19:00 | Cerro Largo-URU | 0 1x3 2 | Universidad Catolica-EQU | 40 | 30 | 30 | 2.35 | 3.14 | 3.08 | |
| 19:00 | Deportivo Tachira-VEN | 0 2x3 2 | LDU Quito-ECU | 29 | 30 | 41 | 3.27 | 3.12 | 2.29 | | | 19:00 | Bahia/BA-BRA | 0 1x3 0 | Nacional-URG | 62 | 23 | 15 | 1.52 | 4.05 | 6.25 | |
| 07/05 | Jogos | | Europa - Uefa Champions - PlayOff |
| 16:00 | Paris St Germain-FRA | 1 2x1 0 | Arsenal-ARG | 46 | 26 | 28 | 2.10 | 3.64 | 3.35 | |
| 07:00 | Shonan Bellmare | 0 0x1 1 | Sanfrecce Hiroshima | 24 | 28 | 48 | 3.83 | 3.35 | 1.98 | | | 07:00 | Machida Zelvia | 1 1x2 0 | Kyoto Sanga | 48 | 28 | 24 | 1.97 | 3.31 | 3.87 | |
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