| |  | | | | | | | | | 21:00 | Liverpool-URU | x | San Lorenzo-ARG | 3.14 | 3.23 | 2.27 | | | 21:00 | Atletico/MG-BRA | x | Penarol-URU | 1.45 | 4.20 | 6.99 | | | 21:30 | Colo Colo-CHI | x | Alianza Lima-PER | 1.49 | 4.02 | 6.63 | |
| | | | | | | | | 10:00 | Orenburg | x | Dinamo Moscow | 3.23 | 3.67 | 2.20 | | | 12:15 | Pari Nizhny | x | Lokomotiv Moscow | 3.70 | 3.53 | 2.00 | |
| | | | | | | | | 13:30 | Hartberg | x | LASK Linz | 3.22 | 3.37 | 2.18 | | | 13:30 | Austria Klagenfurt | x | Salzburg | 7.86 | 4.84 | 1.36 | |
| | | | | | | | | 13:45 | Twente | x | Almere City FC | 1.28 | 5.66 | 10.51 | |
| | | | | | | | | 14:00 | Lorient | x | Paris St Germain | 7.59 | 5.36 | 1.39 | |
| | | | | | | | | 14:30 | Krasnodar | x | Baltika Kaliningrad | 1.70 | 3.79 | 5.11 | | | 14:30 | Zenit St Peterburg | x | Rubin Kazan | 1.34 | 5.06 | 9.34 | |
| | | | | | | | | FT | Sportivo Trinidense-PAR | 12x00 | Nacional Potosi-BOL | 1.48 | 4.24 | 6.16 | | | FT | Deportivo Garcilaso-PER | 01x10 | Cuiaba/MT-BRA | 1.98 | 3.33 | 3.93 | | | FT | Argentinos Juniors-ARG | 11x00 | Corinthians/SP-BRA | 2.91 | 3.11 | 2.54 | |
| | | | | | | | | FT | Junior-COL | 1x1 | LDU Quito-ECU | 2.00 | 3.41 | 3.60 | |
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