| |  | | | | | | | | | 19:00 | Estudiantes-ARG | x | Gremio/RS-BRA | 2.13 | 3.20 | 3.46 | | | 19:00 | Caracas FC-VEN | x | Rosario Central-ARG | 4.06 | 3.44 | 1.88 | | | 21:00 | Liverpool-URU | x | San Lorenzo-ARG | 3.14 | 3.23 | 2.27 | | | 21:00 | Atletico/MG-BRA | x | Penarol-URU | 1.45 | 4.20 | 6.99 | | | 21:30 | Colo Colo-CHI | x | Alianza Lima-PER | 1.49 | 4.02 | 6.63 | |
| | | | | | | | | 10:00 | Orenburg | x | Dinamo Moscow | 3.23 | 3.67 | 2.20 | | | 12:15 | Pari Nizhny | x | Lokomotiv Moscow | 3.70 | 3.53 | 2.00 | |
| | | | | | | | | FT | Union La Calera-CHI | 00x00 | Cruzeiro/MG-BRA | 4.49 | 3.50 | 1.80 | | | FT | Sportivo Trinidense-PAR | 12x00 | Nacional Potosi-BOL | 1.48 | 4.24 | 6.16 | | | FT | Deportivo Garcilaso-PER | 01x10 | Cuiaba/MT-BRA | 1.98 | 3.33 | 3.93 | | | FT | Argentinos Juniors-ARG | 11x00 | Corinthians/SP-BRA | 2.91 | 3.11 | 2.54 | |
| | | | | | | | | FT | Junior-COL | 1x1 | LDU Quito-ECU | 2.00 | 3.41 | 3.60 | |
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