| | | America - Copa Sudamericana |
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| 23:00 | Independiente Medellin-COL | 2 2x1 0 | Defensa y Justicia-ARG | 42 | 30 | 28 | 2.22 | 3.12 | 3.32 |  | | 23:00 | Delfin-ECU | 0 1x2 1 | Internacional/RS-BRA | 23 | 28 | 49 | 4.15 | 3.31 | 1.93 | | | 21:00 | Fortaleza/CE-BRA | 1 4x2 1 | Boca Juniors-ARG | 50 | 28 | 22 | 1.89 | 3.32 | 4.29 | | | 21:00 | Always Ready-BOL | 1 2x0 0 | Cesar Vallejo-PER | 72 | 19 | 09 | 1.29 | 5.03 | 9.95 | | | 19:00 | Nacional Asuncion-PAR | 1 2x2 1 | Racing Club-ARG | 43 | 29 | 28 | 2.18 | 3.19 | 3.35 | | | 19:00 | Metropolitanos-VEN | 0 0x2 2 | Lanus-ARG | 17 | 25 | 58 | 5.32 | 3.72 | 1.63 | |
| 23:00 | Rayo Zuliano-VEN | 0 0x4 2 | Sportivo Ameliano-PAR | 28 | 29 | 43 | 3.34 | 3.19 | 2.18 | | | 21:30 | Real Tomayapo-BOL | 0 0x2 1 | Belgrano-ARG | 16 | 25 | 59 | 5.81 | 3.78 | 1.59 | | | 21:00 | Bragantino/PA-BRA | 1 2x1 0 | Sportivo Luqueno-PAR | 69 | 19 | 12 | 1.35 | 4.84 | 7.95 | | | 19:00 | Danubio-URU | 0 0x1 1 | Athletico/PR-BRA | 23 | 28 | 49 | 4.01 | 3.30 | 1.92 | | | 19:00 | Coquimbo-CHI | 1 1x2 2 | Racing Club-ARG | 22 | 26 | 52 | 4.26 | 3.56 | 1.82 | |
| 21:30 | Argentinos Juniors-ARG | 1 1x0 0 | Corinthians/SP-BRA | 33 | 30 | 37 | 2.91 | 3.11 | 2.54 | | | 21:00 | Sportivo Trinidense-PAR | 1 2x0 0 | Nacional Potosi-BOL | 63 | 22 | 15 | 1.48 | 4.24 | 6.16 | | | 21:00 | Deportivo Garcilaso-PER | 0 1x1 0 | Cuiaba/MT-BRA | 48 | 28 | 24 | 1.98 | 3.33 | 3.93 | | | 19:00 | Union La Calera-CHI | 0 0x0 0 | Cruzeiro/MG-BRA | 21 | 27 | 52 | 4.49 | 3.50 | 1.80 | |
| 21:00 | Cruzeiro/MG-BRA | 3 3x3 0 | Alianza Petrolera-COL | 72 | 19 | 09 | 1.30 | 4.96 | 9.80 | | | 21:00 | Coquimbo-CHI | 1 1x0 0 | Sportivo Luqueno-PAR | 47 | 28 | 25 | 2.01 | 3.28 | 3.73 | | | 19:00 | Metropolitanos-VEN | 0 0x2 2 | Cuiaba/MT-BRA | 23 | 28 | 49 | 4.01 | 3.39 | 1.90 | | | 19:00 | Lanus-ARG | 1 2x1 1 | Deportivo Garcilaso-PER | 78 | 15 | 07 | 1.20 | 6.01 | 13.04 | |
| 23:00 | Independiente Medellin-COL | 2 4x2 0 | Cesar Vallejo-PER | 62 | 23 | 15 | 1.50 | 4.05 | 6.31 | | | 21:30 | Racing Club-ARG | 2 3x0 0 | Bragantino/PA-BRA | 44 | 29 | 27 | 2.15 | 3.20 | 3.41 | | | 21:00 | Union La Calera-CHI | 0 0x1 0 | Universidad Catolica-EQU | 31 | 30 | 39 | 3.00 | 3.15 | 2.40 | | | 21:00 | Internacional/RS-BRA | 0 0x0 0 | Real Tomayapo-BOL | 91 | 06 | 03 | 1.03 | 14.47 | 36.48 | | | 19:00 | Fortaleza/CE-BRA | 3 5x0 0 | Nacional Potosi-BOL | 87 | 09 | 04 | 1.08 | 10.40 | 21.19 | | | 19:00 | Defensa y Justicia-ARG | 1 1x1 0 | Always Ready-BOL | 75 | 17 | 08 | 1.25 | 5.60 | 11.10 | |
| 21:30 | Danubio-URU | 0 0x0 0 | Sportivo Ameliano-PAR | 51 | 28 | 21 | 1.85 | 3.38 | 4.29 | | | 21:30 | Athletico/PR-BRA | 4 6x0 0 | Rayo Zuliano-VEN | 89 | 08 | 03 | 1.06 | 11.56 | 26.74 | | | 21:00 | Boca Juniors-ARG | 0 1x0 0 | Sportivo Trinidense-PAR | 79 | 15 | 06 | 1.19 | 6.21 | 14.37 | | | 19:00 | Corinthians/SP-BRA | 1 4x0 0 | Nacional Asuncion-PAR | 70 | 21 | 09 | 1.35 | 4.56 | 9.41 | | | 19:00 | Argentinos Juniors-ARG | 0 0x3 1 | Racing Club-ARG | 68 | 21 | 11 | 1.38 | 4.43 | 8.24 | |
| 23:00 | Real Tomayapo-BOL | 0 0x2 0 | Delfin-ECU | 25 | 29 | 46 | 3.68 | 3.27 | 2.02 | | | 23:00 | Always Ready-BOL | 1 2x0 0 | Independiente Medellin-COL | 57 | 23 | 20 | 1.64 | 3.97 | 4.73 | | | 21:00 | Univ Catolica-CHI | 0 0x0 0 | Cruzeiro/MG-BRA | 46 | 27 | 27 | 2.03 | 3.41 | 3.49 | | | 21:00 | Sportivo Luqueno-PAR | 0 0x2 2 | Racing Club-ARG | 21 | 26 | 53 | 4.44 | 3.58 | 1.77 | | | 19:00 | Deportivo Garcilaso-PER | 1 3x2 2 | Metropolitanos-VEN | 72 | 18 | 10 | 1.29 | 5.05 | 9.88 | |
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