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| 16:00 | Paris St Germain-FRA | x | Borussia Dortmund-GER | 65 | 20 | 15 | 1.48 | 4.69 | 6.59 |  |
| 19:00 | Caracas FC-VEN | x | Penarol-URU | 19 | 26 | 55 | 4.94 | 3.64 | 1.70 | | | 19:00 | Rosario Central-ARG | x | Atletico/MG-BRA | 28 | 32 | 40 | 3.25 | 2.98 | 2.38 | |
| 19:00 | Nacional Asuncion-PAR | x | Corinthians/SP-BRA | 22 | 27 | 51 | 4.16 | 3.42 | 1.85 | | | 19:00 | Racing Club-URU | x | Argentinos Juniors-ARG | 27 | 30 | 43 | 3.47 | 3.07 | 2.16 | |
| 21:00 | Deportivo Tachira-VEN | x | Libertad-PAR | 23 | 28 | 49 | 4.05 | 3.40 | 1.91 | | | 21:00 | Nacional-URG | x | River Plate-ARG | 26 | 28 | 46 | 3.60 | 3.37 | 2.04 | | | 21:00 | Palestino-CHI | x | Flamengo/RJ-BRA | 13 | 24 | 63 | 6.74 | 4.01 | 1.51 | |
| 21:00 | Cesar Vallejo-PER | x | Independiente Medellin-COL | 28 | 28 | 44 | 3.21 | 3.37 | 2.14 | | | 21:00 | Real Tomayapo-BOL | x | Internacional/RS-BRA | 17 | 23 | 60 | 5.40 | 4.11 | 1.56 | |
| 21:00 | Botafogo/SP | x | Mirassol/SP | 33 | 31 | 36 | 2.88 | 2.97 | 2.57 | |
| 21:30 | Alianza Petrolera-COL | x | Cruzeiro/MG-BRA | 17 | 25 | 58 | 5.28 | 3.79 | 1.61 | | | 21:30 | Sportivo Ameliano-PAR | x | Danubio-URU | 40 | 30 | 30 | 2.36 | 3.07 | 3.07 | |
| 23:00 | Universitario-PER | x | Junior-COL | 43 | 29 | 28 | 2.18 | 3.21 | 3.44 | |
| 23:00 | Always Ready-BOL | x | Defensa y Justicia-ARG | 60 | 23 | 17 | 1.56 | 4.09 | 5.43 | |
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