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| 16:00 | Real Madrid-SPA | x | Bayern Munich-GER | 54 | 24 | 22 | 1.80 | 4.05 | 4.31 |  |
| 19:00 | Huachipato-CHI | x | Gremio/RS-BRA | 25 | 26 | 49 | 3.79 | 3.57 | 1.94 | | | 19:00 | Talleres-ARG | x | Barcelona-ECU | 54 | 25 | 21 | 1.72 | 3.68 | 4.58 | |
| 19:00 | Rayo Zuliano-VEN | x | Athletico/PR-BRA | 13 | 21 | 66 | 7.03 | 4.30 | 1.41 | | | 19:00 | Sportivo Luqueno-PAR | x | Coquimbo-CHI | 42 | 28 | 30 | 2.21 | 3.36 | 3.11 | |
| 21:00 | Alianza Lima-PER | x | Cerro Porteno-PAR | 40 | 30 | 30 | 2.34 | 3.15 | 3.06 | |
| 21:00 | Cuiaba/MT-BRA | x | Metropolitanos-VEN | 74 | 18 | 08 | 1.26 | 5.19 | 10.38 | | | 21:00 | Nacional Potosi-BOL | x | Fortaleza/CE-BRA | 44 | 25 | 31 | 2.14 | 3.68 | 3.00 | |
| 21:00 | America/MG | x | Vila Nova/GO | 56 | 27 | 17 | 1.68 | 3.44 | 5.32 | |
| 21:30 | Botafogo/RJ-BRA | x | LDU Quito-ECU | 59 | 24 | 17 | 1.59 | 4.00 | 5.43 | | | 21:30 | Cobresal-CHI | x | Sao Paulo/SP-BRA | 17 | 24 | 59 | 5.40 | 3.94 | 1.58 | |
| 21:30 | Sportivo Trinidense-PAR | x | Boca Juniors-ARG | 13 | 22 | 65 | 7.00 | 4.25 | 1.43 | |
| 23:00 | Millonarios-COL | x | Bolivar-BOL | 62 | 23 | 15 | 1.51 | 4.06 | 6.06 | |
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